UNC5B (NM_170744) Human Mass Spec Standard

SKU
PH318267
UNC5B MS Standard C13 and N15-labeled recombinant protein (NP_734465)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218267
Predicted MW 103.6 kDa
Protein Sequence
Protein Sequence
>Peptide sequence encoded by RC218267
Blue=ORF Red=Cloning site Green=Tag(s)

MGARSGARGALLLALLLCWDPRLSQAGTDSGSEVLPDSFPSAPAEPLPYFLQEPQDAYIVKNKPVELRC
RAFPATQIYFKCNGEWVSQNDHVTQEGLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSAGT
TKSRRAYVRIAYLRKNFDQEPLGKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPTQDTNFLLTID
HNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNP
APLNGGAFCEGQAFQKTACTTICPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDS
KNCTDGLCMQNKKTLSDPNSHLLEASGDAALYAGLVVAIFVVVAILMAVGVVVYRRNCRDFDTDITDSS
AALTGGFHPVNFKTARPSNPQLLHPSVPPDLTASAGIYRGPVYALQDSTDKIPMTNSPLLDPLPSLKVK
VYSSSTTGSGPGLADGADLLGVLPPGTYPSDFARDTHFLHLRSASLGSQQLLGLPRDPGSSVSGTFGCL
GGRLSIPGTGVSLLVPNGAIPQGKFYEMYLLINKAESTLPLSEGTQTVLSPSVTCGPTGLLLCRPVILT
MPHCAEVSARDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEPRACHILLDQLGTYVFTGESYSRS
AVKRLQLAVFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLMFKDSYHNLRLSLH
DLPHAHWRSKLLAKYQEIPFYHIWSGSQKALHCTFTLERHSLASTELTCKICVRQVEGEGQIFQLHTTL
AETPAGSLDTLCSAPGSTVTTQLGPYAFKIPLSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRYLNYFA
TKASPTGVILDLWEALQQDDGDLNSLASALEEMGKSEMLVAVATDGDC

TRTRPLEQKLISEEDLAANDILDYKDDDDKV

Recombinant protein using RC218267 also available, TP318267
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_734465
RefSeq Size 3935
RefSeq ORF 2835
Synonyms p53RDL1; UNC5H2
Locus ID 219699
UniProt ID Q8IZJ1
Cytogenetics 10q22.1
Summary This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. provided by RefSeq, Oct 2011
Protein Families Druggable Genome, Transmembrane
Protein Pathways Axon guidance
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Other "UNC5B" proteins (3)
SKU Description Size Price
LC406864 Lyophilized UNC5B HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY406864 Transient overexpression lysate of unc-5 homolog B (C. elegans) (UNC5B) (as WB positive control) 100 ug
$665.00
TP318267 Recombinant protein of human unc-5 homolog B (C. elegans) (UNC5B), 20 µg 20 ug
$867.00

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