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COL8A2 (NM_005202) Human Mass Spec Standard

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SKU
PH316003
COL8A2 MS Standard C13 and N15-labeled recombinant protein (NP_005193)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA324440 COL8A2 Antibody (C-term)
400 ul
$645.00
LY401592 Transient overexpression lysate of collagen, type VIII, alpha 2 (COL8A2) (as WB positive control) 100 ug
$665.00

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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216003
Predicted MW 67.24 kDa
Protein Sequence
Protein Sequence
>RC216003 representing NM_005202
Red=Cloning site Green=Tags(s)

MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPL
LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQP
GLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV
GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGV
GVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE
QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP
GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG
PPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGG
KPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKG
TNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL
CPT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005193
RefSeq Size 4443
RefSeq ORF 2109
Synonyms FECD; FECD1; PPCD; PPCD2
Locus ID 1296
UniProt ID P25067
Cytogenetics 1p34.3
Summary This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2014
Protein Families Druggable Genome
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Documents
Resources
Other "COL8A2" proteins (3)
SKU Description Size Price
LC401592 Lyophilized COL8A2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401592 Transient overexpression lysate of collagen, type VIII, alpha 2 (COL8A2) (as WB positive control) 100 ug
$665.00
TP316003 Recombinant protein of human collagen, type VIII, alpha 2 (COL8A2), 20 µg 20 ug
$867.00

file-alt Citations

A cellular model for the investigation of Fuchs' endothelial corneal dystrophy
Kelliher, Chakravarti, Vij et al
Exp. Eye Res. (2011) 93 (6), 880-8 DOI: 10.1016/j.exer.2011.10.001
Cited by 22
AI Summary: OriGene contributed to this study by providing the full-length wild-type human COL8A2 cDNA clone, which was used to create cellular models for investigating Fuchs' endothelial corneal dystrophy.
Snippet: 2.2. COL8A2 expression constructs. A full-length wild-type [WT] human COL8A2 cDNA clone was obtained from OriGene [Rockville, MD]. The full-length identity of this clone was sequence confirmed using primers described by Biswas et al (Biswas et al., 2001).
Showing 1-1 of 1 papers.
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