TLR5 (NM_003268) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC215293 |
| Predicted MW | 97.77 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_003259 |
| RefSeq Size | 3369 |
| RefSeq ORF | 2574 |
| Synonyms | MELIOS; SLE1; SLEB1; TIL3 |
| Locus ID | 7100 |
| UniProt ID | O60602 |
| Cytogenetics | 1q41 |
| Summary | This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.provided by RefSeq, Dec 2009 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Pathogenic Escherichia coli infection, Toll-like receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TLR5" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC401126 | Lyophilized TLR5 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401126 | Transient overexpression lysate of toll-like receptor 5 (TLR5) (as WB positive control) | 100 ug |
$665.00
|
|
| TP315293 | Purified recombinant protein of Homo sapiens toll-like receptor 5 (TLR5), 20 µg | 20 ug |
$867.00
|
|
| TP762255 | Purified recombinant protein of Human toll-like receptor 5 (TLR5), Leu258-Ser404, with N-terminal His-ABP tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
| TP762434 | Purified recombinant protein of Human toll-like receptor 5 (TLR5), Ile21-Val300, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$240.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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