UBE3C (NM_014671) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC215110 |
| Predicted MW | 123.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_055486 |
| RefSeq Size | 5160 |
| RefSeq ORF | 3249 |
| Synonyms | HECTH2 |
| Locus ID | 9690 |
| UniProt ID | Q15386 |
| Cytogenetics | 7q36.3 |
| Summary | E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.UniProtKB/Swiss-Prot Function |
| Protein Families | Druggable Genome |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "UBE3C" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC415125 | Lyophilized UBE3C HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415125 | Transient overexpression lysate of ubiquitin protein ligase E3C (UBE3C) (as WB positive control) | 100 ug |
$665.00
|
|
| TP315110 | Recombinant protein of human ubiquitin protein ligase E3C (UBE3C), 20 µg | 20 ug |
$867.00
|
|
Citations
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