DNMT3A (NM_022552) Human Mass Spec Standard

CAT#: PH313064

DNMT3A MS Standard C13 and N15-labeled recombinant protein (NP_072046)


  View other "DNMT3A" proteins (3)

USD 3,255.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (2)
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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213064
Predicted MW 101.9 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_072046
RefSeq Size 4324
RefSeq ORF 2736
Synonyms DNMT3A2; HESJAS; M.HsaIIIA; TBRS
Locus ID 1788
UniProt ID Q9Y6K1
Cytogenetics 2p23.3
Summary CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Metabolic pathways

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