MSH5 (NM_172166) Human Mass Spec Standard

SKU
PH312608
MSH5 MS Standard C13 and N15-labeled recombinant protein (NP_751898)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212608
Predicted MW 92.7 kDa
Protein Sequence
Protein Sequence
>RC212608 representing NM_172166
Red=Cloning site Green=Tags(s)

MASLGANPRRTPQGPRPGAASSGFPSPAPVPGPREAEEEEVEEEEELAEIHLCVLWNSGYLGIAYYDTSD
STIHFMPDAPDHESLKLLQRVLDEINPQSVVTSAKQDENMTRFLGKLASQEHREPKRPEIIFLPSVDFGL
EISKQRLLSGNYSFIPDAMTATEKILFLSSIIPFDCLLTVRALGGLLKFLGRRRIGVELEDYNVSVPILG
FKKFMLTHLVNIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCHCKWGEKLLRLWFTRPTHD
LGELSSRLDVIQFFLLPQNLDMAQMLHRLLGHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDAC
RSLPQSIQLFRDIAQEFSDDLHHIASLIGKVVDFEGSLAENRFTVLPNIDPEIDEKKRRLMGLPSFLTEV
ARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYRSARTKELDALL
GDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQN
GRHPLMELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDA
IFTRIHSCESISLGLSTFMIDLNQVAKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTC
PHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVAKASHASHTAAQAGLPDKLVAR
GKEVSDLIRSGKPIKPVKDLLKKNQMENCQTLVDKFMKLDLEDPNLDLNVFMSQEVLPAATSIL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_751898
RefSeq Size 3968
RefSeq ORF 2502
Synonyms G7; MUTSH5; NG23; POF13
Locus ID 4439
UniProt ID O43196
Cytogenetics 6p21.33
Summary This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. provided by RefSeq, Feb 2011
Protein Families Druggable Genome
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Other "MSH5" proteins (7)
SKU Description Size Price
PH300607 MSH5 MS Standard C13 and N15-labeled recombinant protein (NP_002432) 10 ug
$3,360.00
LC406777 Lyophilized MSH5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419330 Lyophilized MSH5 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY406777 Transient overexpression lysate of mutS homolog 5 (E. coli) (MSH5), transcript variant 4 (as WB positive control) 100 ug
$665.00
LY419330 Transient overexpression lysate of mutS homolog 5 (E. coli) (MSH5), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP300607 Recombinant protein of human mutS homolog 5 (E. coli) (MSH5), transcript variant 3, 20 µg 20 ug
$867.00
TP312608 Recombinant protein of human mutS homolog 5 (E. coli) (MSH5), transcript variant 4, 20 µg 20 ug
$867.00

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