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RASGRP1 (NM_005739) Human Mass Spec Standard

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SKU
PH312473
RASGRP1 MS Standard C13 and N15-labeled recombinant protein (NP_005730)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA358534 RASGRP1 Antibody - C-terminal region
100 ul
$585.00
LY417099 Transient overexpression lysate of RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1 (as WB positive control) 100 ug
$665.00

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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212473
Predicted MW 90.4 kDa
Protein Sequence
Protein Sequence
>RC212473 protein sequence
Red=Cloning site Green=Tags(s)

MGTLGKAREAPRKPSHGCRAASKARLEAKPANSPFPSHPSLAHITQFRMMVSLGHLAKGASLDDLIDSCI
QSFDADGNLCRSNQLLQVMLTMHRIVISSAELLQKVITLYKDALAKNSPGLCLKICYFVRYWITEFWVMF
KMDASLTDTMEEFQELVKAKGEELHCRLIDTTQINARDWSRKLTQRIKSNTSKKRKVSLLFDHLEPEELS
EHLTYLEFKSFRRISFSDYQNYLVNSCVKENPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIQ
VAQKLHQLQNFNTLMAVIGGLCHSSISRLKETSSHVPHEINKVLGEMTELLSSSRNYDNYRRAYGECTDF
KIPILGVHLKDLISLYEAMPDYLEDGKVNVHKLLALYNHISELVQLQEVAPPLEANKDLVHLLTLSLDLY
YTEDEIYELSYAREPRNHRAPPLTPSKPPVVVDWASGVSPKPDPKTISKHVQRMVDSVFKNYDHDQDGYI
SQEEFEKIAASFPFSFCVMDKDREGLISRDEITAYFMRASSIYSKLGLGFPHNFQETTYLKPTFCDNCAG
FLWGVIKQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAPTENNTSVGPVSNLCSLGAKDLLHAPEEGP
FTFPNGEAVEHGEESKDRTIMLMGVSSQKISLRLKRAVAHKATQTESQPWIGSEGPSGPFVLSSPRKTAQ
DTLYVLPSPTSPCPSPVLVRKRAFVKWENKDSLIKSKEELRHLRLPTYQELEQEINTLKADNDALKIQLK
YAQKKIESLQLEKSNHVLAQMEQGDCS

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005730
RefSeq Size 5048
RefSeq ORF 2391
Synonyms CALDAG-GEFI; CALDAG-GEFII; IMD64; RASGRP
Locus ID 10125
UniProt ID O95267
Cytogenetics 15q14
Summary This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). provided by RefSeq, Jul 2008
Protein Pathways MAPK signaling pathway, T cell receptor signaling pathway
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Other "RASGRP1" proteins (3)
SKU Description Size Price
LC417099 Lyophilized RASGRP1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417099 Transient overexpression lysate of RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP312473 Recombinant protein of human RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), transcript variant 1, 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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