PDE4D (NM_006203) Human Mass Spec Standard

SKU
PH312410
PDE4D MS Standard C13 and N15-labeled recombinant protein (NP_006194)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC212410
Predicted MW 76.3 kDa
Protein Sequence
Protein Sequence
>RC212410 representing NM_006203
Red=Cloning site Green=Tags(s)

MHVNNFPFRRHSWICFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMS
RNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLA
SETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIP
SPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGN
RPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVF
TDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKK
QRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKP
LQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDI
LDTLEDNREWYQSTIPQSPSPAPDDPEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKT
LCTQDSESTEIPLDEQVEEEAVGEEEESQPEACVIDDRSPDT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006194
RefSeq Size 5876
RefSeq ORF 2016
Synonyms ACRDYS2; DPDE3; HSPDE4D; PDE4DN2; PDE43; STRK1
Locus ID 5144
UniProt ID Q08499
Cytogenetics 5q11.2-q12.1
Summary This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.provided by RefSeq, Sep 2009
Protein Families Druggable Genome
Protein Pathways Progesterone-mediated oocyte maturation, Purine metabolism
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Other "PDE4D" proteins (7)
SKU Description Size Price
LC401868 Lyophilized PDE4D HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434324 Lyophilized PDE4D HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC434368 Lyophilized PDE4D HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401868 Transient overexpression lysate of phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) (PDE4D), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY434324 Transient overexpression lysate of phosphodiesterase 4D, cAMP-specific (PDE4D), transcript variant 8 (as WB positive control) 100 ug
$436.00
LY434368 Transient overexpression lysate of phosphodiesterase 4D, cAMP-specific (PDE4D), transcript variant 6 (as WB positive control) 100 ug
$665.00
TP312410 Recombinant protein of human phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) (PDE4D), transcript variant 2, 20 µg 20 ug
$737.00

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