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HSPC142 (BABAM1) (NM_001033549) Human Mass Spec Standard

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SKU
PH310626
C19orf62 MS Standard C13 and N15-labeled recombinant protein (NP_001028721)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA890052 Rabbit polyclonal anti-BABAM1 Antibody
100 ul
$407.00
LY415463 Transient overexpression lysate of chromosome 19 open reading frame 62 (C19orf62), transcript variant 2 (as WB positive control) 100 ug
$436.00

Other products for "HSPC142 or NM_001033549"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210626
Predicted MW 36.6 kDa
Protein Sequence
Protein Sequence
>RC210626 protein sequence
Red=Cloning site Green=Tags(s)

MEVAEPSSPTEEEEEEEEHSAEPRPRTRSNPEGAEDRAVGAQASVGSRSEGEGEAASADDGSLNTSGAGP
KSWQVPPPAPEVQIRTPRVNCPEKVIICLDLSEEMSLPKLESFNGSKTNALNVSQKMIEMFVRTKHKIDK
SHEFALVVVNDDTAWLSGLTSDPRELCSCLYDLETASCSTFNLEGLFSLIQQKTELPVTENVQTIPPPYV
VRTILVYSRPPCQPQFSLTEPMKKMFQCPYFFFDVVYIHNGTEEKEEEMSWKDMFAFMGSLDTKGTSYKY
EVALAGPALELHNCMAKLLAHPLQRPCQSHASYSLLEEEDEAIEVEATV

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001028721
RefSeq Size 1505
RefSeq ORF 987
Synonyms C19orf62; HSPC142; MERIT40; NBA1
Locus ID 29086
UniProt ID Q9NWV8
Cytogenetics 19p13.11
Summary Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates (PubMed:24075985, PubMed:26195665). In these 2 complexes, it is probably required to maintain the stability of BABAM2 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665). Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression (PubMed:24075985). Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985).UniProtKB/Swiss-Prot Function
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Other "HSPC142" proteins (7)
SKU Description Size Price
PH302644 C19orf62 MS Standard C13 and N15-labeled recombinant protein (NP_054892) 10 ug
$3,360.00
LC415463 Lyophilized BABAM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC422382 Lyophilized BABAM1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415463 Transient overexpression lysate of chromosome 19 open reading frame 62 (C19orf62), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY422382 Transient overexpression lysate of chromosome 19 open reading frame 62 (C19orf62), transcript variant 1 (as WB positive control) 100 ug
$436.00
TP302644 Recombinant protein of human chromosome 19 open reading frame 62 (C19orf62), transcript variant 2, 20 µg 20 ug
$867.00
TP310626 Recombinant protein of human chromosome 19 open reading frame 62 (C19orf62), transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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