IL2 (NM_000586) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC210013 |
| Predicted MW | 17.6 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000577 |
| RefSeq Size | 822 |
| RefSeq ORF | 459 |
| Synonyms | IL-2; lymphokine; TCGF |
| Locus ID | 3558 |
| UniProt ID | P60568 |
| Cytogenetics | 4q27 |
| Summary | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. provided by RefSeq, Sep 2020 |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "IL2" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC424619 | Lyophilized IL2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424619 | Transient overexpression lysate of interleukin 2 (IL2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP310013 | Recombinant protein of human interleukin 2 (IL2), 20 µg | 20 ug |
$867.00
|
|
| TP720012 | Recombinant protein of human interleukin 2 (IL2), Pro22-Thr153 | 10 ug |
$190.00
|
|
| TP723850 | Purified recombinant protein of Human interleukin 2 (IL2) | 10 ug |
$345.00
|
|
| TP750020 | Purified recombinant protein of Homo sapiens Interleukin 2 (IL-2) produced in E. coli. | 100 ug |
$540.00
|
|
| TP790117 | Purified recombinant protein of Human interleukin 2 (IL2), Tag free, secretory expressed in CHO cells, 100ug | 100 ug |
$540.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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