AK2 (NM_001625) Human Mass Spec Standard

SKU
PH309974
AK2 MS Standard C13 and N15-labeled recombinant protein (NP_001616)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209974
Predicted MW 26.5 kDa
Protein Sequence
Protein Sequence
>RC209974 protein sequence
Red=Cloning site Green=Tags(s)

MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDA
GKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRIT
GRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAI
DASQTPDVVFASILAAFSKATCKDLVMFI

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001616
RefSeq Size 2759
RefSeq ORF 717
Synonyms ADK2
Locus ID 204
UniProt ID P54819
Cytogenetics 1p35.1
Summary Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.provided by RefSeq, Nov 2010
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism
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Other "AK2" proteins (5)
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LC415600 Lyophilized AK2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY415600 Transient overexpression lysate of adenylate kinase 2 (AK2), transcript variant AK2B (as WB positive control) 100 ug
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LY419835 Transient overexpression lysate of adenylate kinase 2 (AK2), transcript variant AK2A (as WB positive control) 100 ug
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TP309974 Recombinant protein of human adenylate kinase 2 (AK2), transcript variant AK2A, 20 µg 20 ug
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