COQ3 (NM_017421) Human Mass Spec Standard

SKU
PH309576
COQ3 MS Standard C13 and N15-labeled recombinant protein (NP_059117)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209576
Predicted MW 41 kDa
Protein Sequence
Protein Sequence
>RC209576 protein sequence
Red=Cloning site Green=Tags(s)

MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSC
LNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQ
PGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVE
ETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHT
WEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAHAVKSRVQEHPASAEFVLKGET
EELQANACTNPAVHEKLKK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_059117
RefSeq Size 1265
RefSeq ORF 1107
Synonyms bA9819.1; DHHBMT; DHHBMTASE; UG0215E05
Locus ID 51805
UniProt ID Q9NZJ6
Cytogenetics 6q16.2
Summary Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 PubMed 10777520). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.supplied by OMIM, Mar 2008
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Ubiquinone and other terpenoid-quinone biosynthesis
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Other "COQ3" proteins (3)
SKU Description Size Price
LC413779 Lyophilized COQ3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY413779 Transient overexpression lysate of coenzyme Q3 homolog, methyltransferase (S. cerevisiae) (COQ3) (as WB positive control) 100 ug
$436.00
TP309576 Recombinant protein of human coenzyme Q3 homolog, methyltransferase (S. cerevisiae) (COQ3), 20 µg 20 ug
$867.00

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