THOC7 (NM_025075) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC209500 |
| Predicted MW | 23.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_079351 |
| RefSeq Size | 1027 |
| RefSeq ORF | 612 |
| Synonyms | fSAP24; hTREX30; NIF3L1BP1 |
| Locus ID | 80145 |
| UniProt ID | Q6I9Y2 |
| Cytogenetics | 3p14.1 |
| Summary | Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "THOC7" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC410901 | Lyophilized THOC7 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY410901 | Transient overexpression lysate of THO complex 7 homolog (Drosophila) (THOC7) (as WB positive control) | 100 ug |
$436.00
|
|
| TP309500 | Recombinant protein of human THO complex 7 homolog (Drosophila) (THOC7), 20 µg | 20 ug |
$867.00
|
|
Citations
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