DUSP9 (NM_001395) Human Mass Spec Standard

SKU
PH309271
DUSP9 MS Standard C13 and N15-labeled recombinant protein (NP_001386)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209271
Predicted MW 41.9 kDa
Protein Sequence
Protein Sequence
>RC209271 protein sequence
Red=Cloning site Green=Tags(s)

MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL
QPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCET
SLAGRAGSSMAPLPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPN
LYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEAL
SQNRGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERH
SQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001386
RefSeq Size 2394
RefSeq ORF 1152
Synonyms MKP-4; MKP4
Locus ID 1852
UniProt ID Q99956
Cytogenetics Xq28
Summary The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jan 2016
Protein Families Phosphatase
Protein Pathways MAPK signaling pathway
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Other "DUSP9" proteins (3)
SKU Description Size Price
LC419956 Lyophilized DUSP9 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419956 Transient overexpression lysate of dual specificity phosphatase 9 (DUSP9) (as WB positive control) 100 ug
$436.00
TP309271 Recombinant protein of human dual specificity phosphatase 9 (DUSP9), 20 µg 20 ug
$737.00

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