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SIGLEC8 (NM_014442) Human Mass Spec Standard

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SKU
PH308582
SIGLEC8 MS Standard C13 and N15-labeled recombinant protein (NP_055257)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA351666 Rabbit Polyclonal Anti-SIGLEC8 Antibody
100 ul
$205.00
LY415267 Transient overexpression lysate of sialic acid binding Ig-like lectin 8 (SIGLEC8) (as WB positive control) 100 ug
$436.00

Other products for "SIGLEC8 or NM_014442"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC208582
Predicted MW 54.1 kDa
Protein Sequence
Protein Sequence
>RC208582 protein sequence
Red=Cloning site Green=Tags(s)

MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAG
DRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLN
YKTKQLSVFVTALTHRPDILILGTLESGHPRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLT
LTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLR
LVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGT
GTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIVRSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTE
SWKDGNPLKKPPPAVAPSSGEEGELHYATLSFHKVKPQDPQGQEATDSEYSEIKIHKRETAETQACLRNH
NPSSKEVRG

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055257
RefSeq Size 2967
RefSeq ORF 1497
Synonyms SAF2; SIGLEC-8; SIGLEC8L
Locus ID 27181
UniProt ID Q9NYZ4
Cytogenetics 19q13.41
Summary Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 PubMed 11095983).supplied by OMIM, May 2010
Protein Families Druggable Genome, Transmembrane
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Other "SIGLEC8" proteins (3)
SKU Description Size Price
LC415267 Lyophilized SIGLEC8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY415267 Transient overexpression lysate of sialic acid binding Ig-like lectin 8 (SIGLEC8) (as WB positive control) 100 ug
$436.00
TP308582 Recombinant protein of human sialic acid binding Ig-like lectin 8 (SIGLEC8), 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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