CD299 (CLEC4M) (NM_014257) Human Mass Spec Standard

SKU
PH307947
CLEC4M MS Standard C13 and N15-labeled recombinant protein (NP_055072)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207947
Predicted MW 45.4 kDa
Protein Sequence
Protein Sequence
>RC207947 protein sequence
Red=Cloning site Green=Tags(s)

MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFMLLAGVLVAILV
QVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELT
RLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTE
LKAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCY
FMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPS
FQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055072
RefSeq Size 1976
RefSeq ORF 1197
Synonyms CD209L; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN
Locus ID 10332
UniProt ID Q9H2X3
Cytogenetics 19p13.2
Summary This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. provided by RefSeq, May 2020
Protein Families Druggable Genome, Transmembrane
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Other "CD299" proteins (7)
SKU Description Size Price
PH311716 CLEC4M MS Standard C13 and N15-labeled recombinant protein (NP_999840) 10 ug
$3,360.00
LC402300 Lyophilized CLEC4M HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC403743 Lyophilized CLEC4M HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402300 Transient overexpression lysate of C-type lectin domain family 4, member M (CLEC4M), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY403743 Transient overexpression lysate of C-type lectin domain family 4, member M (CLEC4M), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP307947 Recombinant protein of human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, 20 µg 20 ug
$867.00
TP311716 Purified recombinant protein of Homo sapiens C-type lectin domain family 4, member M (CLEC4M), transcript variant 2, 20 µg 20 ug
$867.00

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