P2RX4 (NM_002560) Human Mass Spec Standard

SKU
PH307613
P2RX4 MS Standard C13 and N15-labeled recombinant protein (NP_002551)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207613
Predicted MW 43.3 kDa
Protein Sequence
Protein Sequence
>RC207613 protein sequence
Red=Cloning site Green=Tags(s)

MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKVKG
VAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTH
SNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNIT
TTYLKSCIYDAKTDPFCPIFRLGKIVENAGHGFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLD
TRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMAT
VLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_002551
RefSeq Size 2043
RefSeq ORF 1164
Synonyms P2X4; P2X4R
Locus ID 5025
UniProt ID Q99571
Cytogenetics 12q24.31
Summary The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. provided by RefSeq, Feb 2012
Protein Families Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
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Other "P2RX4" proteins (3)
SKU Description Size Price
LC419264 Lyophilized P2RX4 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419264 Transient overexpression lysate of purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4) (as WB positive control) 100 ug
$436.00
TP307613 Recombinant protein of human purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4), 20 µg 20 ug
$737.00

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