ARRDC1 (NM_152285) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC207160 |
| Predicted MW | 46 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_689498 |
| RefSeq Size | 1621 |
| RefSeq ORF | 1299 |
| Locus ID | 92714 |
| UniProt ID | Q8N5I2 |
| Cytogenetics | 9q34.3 |
| Summary | Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ARRDC1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC407667 | Lyophilized ARRDC1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY407667 | Transient overexpression lysate of arrestin domain containing 1 (ARRDC1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP307160 | Recombinant protein of human arrestin domain containing 1 (ARRDC1), 20 µg | 20 ug |
$737.00
|
|
Citations
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