BMPR1A (NM_004329) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC206048 |
| Predicted MW | 60.2 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004320 |
| RefSeq Size | 3631 |
| RefSeq ORF | 1596 |
| Synonyms | 10q23del; ACVRLK3; ALK3; CD292; SKR5 |
| Locus ID | 657 |
| UniProt ID | P36894 |
| Cytogenetics | 10q23.2 |
| Summary | The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. provided by RefSeq, Jul 2008 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "BMPR1A" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC418061 | Lyophilized BMPR1A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY418061 | Transient overexpression lysate of bone morphogenetic protein receptor, type IA (BMPR1A) (as WB positive control) | 100 ug |
$436.00
|
|
| TP306048 | Recombinant protein of human bone morphogenetic protein receptor, type IA (BMPR1A), 20 µg | 20 ug |
$737.00
|
|
Citations
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