MTHFS (NM_006441) Human Mass Spec Standard

CAT#: PH305749

MTHFS MS Standard C13 and N15-labeled recombinant protein (NP_006432)


  View other "MTHFS" proteins (4)

USD 3,255.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
Transient overexpression lysate of 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) (MTHFS)
    • 100 ug

USD 436.00

Other products for "MTHFS"

Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205749
Predicted MW 23.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_006432
RefSeq Size 2346
RefSeq ORF 609
Synonyms HsT19268; NEDMEHM
Locus ID 10588
UniProt ID P49914
Cytogenetics 15q25.1
Summary The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Protein Pathways Metabolic pathways, One carbon pool by folate

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