SAP18 (NM_005870) Human Mass Spec Standard

SKU
PH305607
SAP18 MS Standard C13 and N15-labeled recombinant protein (NP_005861)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC205607
Predicted MW 17.6 kDa
Protein Sequence
Protein Sequence
>RC205607 protein sequence
Red=Cloning site Green=Tags(s)

MAVESRVTQEEIKKEPEKPIDREKTCPLLLRVFTTNNGRHHRMDEFSRGNVPSSELQIYTWMDATLKELT
SLVKEVYPEARKKGTHFNFAIVFTDVKRPGYRVKEIGSTMSGRKGTDDSMTLQSQKFQIGDYLDIAITPP
NRAPPTSGRMRPY

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005861
RefSeq Size 2318
RefSeq ORF 459
Synonyms 2HOR0202; SAP18P
Locus ID 10284
UniProt ID O00422
Cytogenetics 13q12.11
Summary Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. provided by RefSeq, Dec 2008
Protein Families Druggable Genome, Transcription Factors
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Other "SAP18" proteins (3)
SKU Description Size Price
LC417012 Lyophilized SAP18 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY417012 Transient overexpression lysate of Sin3A-associated protein, 18kDa (SAP18) (as WB positive control) 100 ug
$436.00
TP305607 Recombinant protein of human Sin3A-associated protein, 18kDa (SAP18), 20 µg 20 ug
$867.00

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