FGD1 (NM_004463) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC205133 |
| Predicted MW | 106.4 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_004454 |
| RefSeq Size | 4291 |
| RefSeq ORF | 2883 |
| Synonyms | AAS; FGDY; MRXS16; ZFYVE3 |
| Locus ID | 2245 |
| UniProt ID | P98174 |
| Cytogenetics | Xp11.22 |
| Summary | This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of the faciogenital dysplasia in Aarskog-Scott syndrome and a syndromatic form of X-linked cognitive disability. provided by RefSeq, Jul 2017 |
| Protein Pathways | Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "FGD1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC417971 | Lyophilized FGD1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY417971 | Transient overexpression lysate of FYVE, RhoGEF and PH domain containing 1 (FGD1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP305133 | Recombinant protein of human FYVE, RhoGEF and PH domain containing 1 (FGD1), 20 µg | 20 ug |
$867.00
|
|
Citations
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