MVB12B (NM_001011703) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC205093 |
| Predicted MW | 24.5 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001011703 |
| RefSeq Size | 2705 |
| RefSeq ORF | 663 |
| Synonyms | C9orf28; FAM125B |
| Locus ID | 89853 |
| UniProt ID | Q9H7P6 |
| Cytogenetics | 9q33.3 |
| Summary | The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Aug 2011 |
| Protein Pathways | Endocytosis |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "MVB12B" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC409511 | Lyophilized MVB12B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC423295 | Lyophilized MVB12B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409511 | Transient overexpression lysate of family with sequence similarity 125, member B (FAM125B), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY423295 | Transient overexpression lysate of family with sequence similarity 125, member B (FAM125B), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP305093 | Recombinant protein of human family with sequence similarity 125, member B (FAM125B), transcript variant 2, 20 µg | 20 ug |
$867.00
|
|
Citations
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