PLEKHF2 (NM_024613) Human Mass Spec Standard

SKU PH303964

PLEKHF2 MS Standard C13 and N15-labeled recombinant protein (NP_078889)

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: [RC203964]
• Predicted MW: 27.8 kDa
• Protein Sequence:
  Protein Sequence

  >RC203964 protein sequence; Red=Cloning site Green=Tags(s); ; MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQ; KKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKT; PSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDL; LSAGDMATCQPARSDSYSQSLKSPLNDMSDDDDDDDSSD; ; TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_078889
• RefSeq Size: 2977
• RefSeq ORF: 747
• Synonyms: EAPF; PHAFIN2; ZFYVE18
• Locus ID: 79666
• UniProt ID: Q9H8W4
• Cytogenetics: 8q22.1
• Summary: May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).[UniProtKB/Swiss-Prot Function]