VASP (NM_003370) Human Mass Spec Standard

CAT#: PH303544

VASP MS Standard C13 and N15-labeled recombinant protein (NP_003361)

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USD 1,995.00

3 Weeks

    • 10 ug

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Product Data
Description VASP MS Standard C13 and N15-labeled recombinant protein (NP_003361)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203544
Predicted MW 40.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_003361
RefSeq Size 2298
RefSeq ORF 1140
Synonyms vasodilator-stimulated phosphoprotein
Locus ID 7408
Cytogenetics 19q13.32
Summary Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008].
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