DCPS (NM_014026) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC203052 |
| Predicted MW | 38.7 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_054745 |
| RefSeq Size | 1508 |
| RefSeq ORF | 1011 |
| Synonyms | ARS; DCS1; HINT-5; HINT5; HSL1; HSPC015 |
| Locus ID | 28960 |
| UniProt ID | Q96C86 |
| Cytogenetics | 11q24.2 |
| Summary | This gene encodes a member of the histidine triad family of pyrophosphatases that removes short mRNA fragments containing the 5′ mRNA cap structure, which appear in the 3′ → 5′ mRNA decay pathway, following deadenylation and exosome-mediated turnover. This enzyme hydrolyzes the triphosphate linkage of the cap structure (7-methylguanosine nucleoside triphosphate) to yield 7-methylguanosine monophosphate and nucleoside diphosphate. It protects the cell from the potentially toxic accumulation of these short, capped mRNA fragments, and regulates the activity of other cap-binding proteins, which are inhibited by their accumulation. It also acts as a transcript-specific modulator of pre-mRNA splicing and microRNA turnover. provided by RefSeq, Apr 2017 |
| Protein Pathways | RNA degradation |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "DCPS" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC415527 | Lyophilized DCPS HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY415527 | Transient overexpression lysate of decapping enzyme, scavenger (DCPS) (as WB positive control) | 100 ug |
$436.00
|
|
| TP303052 | Recombinant protein of human decapping enzyme, scavenger (DCPS), 20 µg | 20 ug |
$737.00
|
|
Citations
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