TDO2 (NM_005651) Human Mass Spec Standard

SKU
PH302777
TDO2 MS Standard C13 and N15-labeled recombinant protein (NP_005642)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202777
Predicted MW 47.9 kDa
Protein Sequence
Protein Sequence
>RC202777 protein sequence
Red=Cloning site Green=Tags(s)

MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSETKGNKIHDEH
LFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDF
NDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEENELLLKSEQEKTLLELVEAWLE
RTPGLEPHGFNFWGKLEKNITRGLEEEFIRIQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKG
ERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHY
LRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSSDESD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_005642
RefSeq Size 1703
RefSeq ORF 1218
Synonyms HYPTRP; TDO; TO; TPH2; TRPO
Locus ID 6999
UniProt ID P48775
Cytogenetics 4q32.1
Summary This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. provided by RefSeq, Feb 2012
Protein Pathways Metabolic pathways, Tryptophan metabolism
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Other "TDO2" proteins (3)
SKU Description Size Price
LC401726 Lyophilized TDO2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY401726 Transient overexpression lysate of tryptophan 2,3-dioxygenase (TDO2) (as WB positive control) 100 ug
$436.00
TP302777 Recombinant protein of human tryptophan 2,3-dioxygenase (TDO2), 20 µg 20 ug
$867.00

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