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GM2A (NM_000405) Human Mass Spec Standard

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SKU
PH302452
GM2A MS Standard C13 and N15-labeled recombinant protein (NP_000396)
Size:
10 ug
  $3,360.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (1)

LY400143 Transient overexpression lysate of GM2 ganglioside activator (GM2A), transcript variant 1 (as WB positive control) 100 ug
$436.00

Other products for "GM2A or NM_000405"

Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202452
Predicted MW 20.8 kDa
Protein Sequence
Protein Sequence
>RC202452 protein sequence
Red=Cloning site Green=Tags(s)

MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIVVPGNVTLSVVG
STSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPF
KEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_000396
RefSeq Size 3690
RefSeq ORF 579
Synonyms GM2-AP; SAP-3
Locus ID 2760
UniProt ID P17900
Cytogenetics 5q33.1
Summary This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. provided by RefSeq, Nov 2009
Protein Families Druggable Genome
Protein Pathways Lysosome
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Other "GM2A" proteins (5)
SKU Description Size Price
LC400143 Lyophilized GM2A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC432647 Lyophilized GM2A HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400143 Transient overexpression lysate of GM2 ganglioside activator (GM2A), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY432647 Transient overexpression lysate of GM2 ganglioside activator (GM2A), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP302452 Recombinant protein of human GM2 ganglioside activator (GM2A), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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