BIN1 (NM_139350) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC202423 |
| Predicted MW | 48.3 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_647600 |
| RefSeq Size | 2224 |
| RefSeq ORF | 1317 |
| Synonyms | AMPH2; AMPHL; CNM2; SH3P9 |
| Locus ID | 274 |
| UniProt ID | O00499 |
| Cytogenetics | 2q14.3 |
| Summary | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. provided by RefSeq, Mar 2016 |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "BIN1" proteins (21)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH320585 | BIN1 MS Standard C13 and N15-labeled recombinant protein (NP_647594) | 10 ug |
$3,360.00
|
|
| PH320616 | BIN1 MS Standard C13 and N15-labeled recombinant protein (NP_004296) | 10 ug |
$3,360.00
|
|
| LC403388 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408302 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408303 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408305 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408306 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408307 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC408308 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC418073 | Lyophilized BIN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403388 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 9 (as WB positive control) | 100 ug |
$436.00
|
|
| LY408302 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408303 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408305 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 4 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408306 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 5 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408307 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 6 (as WB positive control) | 100 ug |
$665.00
|
|
| LY408308 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 7 (as WB positive control) | 100 ug |
$665.00
|
|
| LY418073 | Transient overexpression lysate of bridging integrator 1 (BIN1), transcript variant 8 (as WB positive control) | 100 ug |
$665.00
|
|
| TP302423 | Recombinant protein of human bridging integrator 1 (BIN1), transcript variant 9, 20 µg | 20 ug |
$737.00
|
|
| TP320585 | Recombinant protein of human bridging integrator 1 (BIN1), transcript variant 2, 20 µg | 20 ug |
$737.00
|
|
| TP320616 | Recombinant protein of human bridging integrator 1 (BIN1), transcript variant 8, 20 µg | 20 ug |
$737.00
|
|
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