AGR2 (NM_006408) Human Mass Spec Standard

SKU
PH302023
AGR2 MS Standard C13 and N15-labeled recombinant protein (NP_006399)
  $3,360.00
3 Weeks*
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Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202023
Predicted MW 19.8 kDa
Protein Sequence
Protein Sequence
>RC202023 representing NM_006408
Red=Cloning site Green=Tags(s)

MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNK
PLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSPDGQYVPRIMFVDPSLTVRAD
ITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_006399
RefSeq Size 1701
RefSeq ORF 525
Synonyms AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; XAG-2
Locus ID 10551
UniProt ID O95994
Cytogenetics 7p21.1
Summary This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. provided by RefSeq, Mar 2017
Protein Families Secreted Protein
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Other "AGR2" proteins (4)
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LC416668 Lyophilized AGR2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY416668 Transient overexpression lysate of anterior gradient homolog 2 (Xenopus laevis) (AGR2) (as WB positive control) 100 ug
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TP302023 Recombinant protein of human anterior gradient homolog 2 (Xenopus laevis) (AGR2), 20 µg 20 ug
$867.00
TP720358 Recombinant protein of human anterior gradient homolog 2 (Xenopus laevis) (AGR2) 10 ug
$275.00

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