TGIF (TGIF1) (NM_173208) Human Mass Spec Standard

SKU
PH301549
TGIF1 MS Standard C13 and N15-labeled recombinant protein (NP_775300)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201549
Predicted MW 29.7 kDa
Protein Sequence
Protein Sequence
>RC201549 protein sequence
Red=Cloning site Green=Tags(s)

MKGKKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKAL
LSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETP
FHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTD
TSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_775300
RefSeq Size 1890
RefSeq ORF 816
Synonyms HPE4; TGIF
Locus ID 7050
UniProt ID Q15583
Cytogenetics 18p11.31
Summary The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. provided by RefSeq, Jul 2013
Protein Families Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
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LC430396 Lyophilized TGIF1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
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LY406653 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3 (as WB positive control) 100 ug
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LY406654 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 5 (as WB positive control) 100 ug
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LY406655 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 6 (as WB positive control) 100 ug
$436.00
LY406656 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 7 (as WB positive control) 100 ug
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LY406799 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 1 (as WB positive control) 100 ug
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LY418813 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4 (as WB positive control) 100 ug
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LY429136 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4 (as WB positive control) 100 ug
$436.00
LY430396 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 2 (as WB positive control) 100 ug
$436.00
LY430398 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 7 (as WB positive control) 100 ug
$436.00
TP301549 Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3, 20 µg 20 ug
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TP760015 Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
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TP760299 Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
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TP760446 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 6, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
$270.00
TP760754 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00
TP760828 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00
TP760837 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 5, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
$270.00

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