TGIF (TGIF1) (NM_174886) Human Recombinant Protein

SKU
TP760299
Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
  $270.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding human full-length TGIF1
Tag N-His
Predicted MW 27.5 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_777480
Locus ID 7050
UniProt ID Q15583
Cytogenetics 18p11.31
RefSeq Size 1687
RefSeq ORF 756
Synonyms HPE4; TGIF
Summary The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. provided by RefSeq, Jul 2013
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Stem cell - Pluripotency, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
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LY406655 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 6 (as WB positive control) 100 ug
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LY418813 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4 (as WB positive control) 100 ug
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LY429136 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4 (as WB positive control) 100 ug
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LY430396 Transient overexpression lysate of TGFB-induced factor homeobox 1 (TGIF1), transcript variant 2 (as WB positive control) 100 ug
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TP301549 Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3, 20 µg 20 ug
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TP760015 Recombinant protein of human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
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TP760446 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 6, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug 50 ug
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TP760754 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 4, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
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TP760828 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
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TP760837 Purified recombinant protein of Human TGFB-induced factor homeobox 1 (TGIF1), transcript variant 5, full length, with N-terminal HIS tag, expressed in E. coli, 50ug 50 ug
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