M6PR (NM_002355) Human Mass Spec Standard

CAT#: PH301277

M6PR MS Standard C13 and N15-labeled recombinant protein (NP_002346)

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USD 1,995

3 Weeks

    • 10 ug

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Product Data
Description M6PR MS Standard C13 and N15-labeled recombinant protein (NP_002346)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201277
Predicted MW 30.99 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_002346
RefSeq Size 2454
RefSeq ORF 831
Synonyms CD-MPR; MPR 46; MPR-46; MPR46; SMPR
Locus ID 4074
Cytogenetics 12p13.31
Summary Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. [UniProtKB/Swiss-Prot Function]
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