PSME1 (NM_006263) Human Mass Spec Standard

CAT#: PH301260

Reviews ()
Write a review

PSME1 MS Standard C13 and N15-labeled recombinant protein (NP_006254)


Product Datasheet for 'PH301260'


  View other "PSME1" proteins (3)

USD 2,055.00


Availability*
3 Weeks

Size
    • 10 ug


Product images

Specifications

Product Data
Description PSME1 MS Standard C13 and N15-labeled recombinant protein (NP_006254)
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201260
Predicted MW 28.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_006254
RefSeq Size 1023
RefSeq ORF 747
Synonyms HEL-S-129m; IFI5111; PA28A; PA28alpha; REGalpha
Locus ID 5720
Cytogenetics 14q12
Summary The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Protein Pathways Antigen processing and presentation, Proteasome

Documents

Other Versions

Other products for "PSME1"
Frequently bought together (2)
Transient overexpression lysate of proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1), transcript variant 1
    • 100 ug

USD 325.00


Rabbit anti-PSME1 Polyclonal Antibody
    • 100 ul

USD 345.00

Customer Reviews 
Loading...
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
68 Mouse Clones
Molbio tools