GMDS (NM_001500) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200471 |
| Predicted MW | 41.9 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001491 |
| RefSeq Size | 1700 |
| RefSeq ORF | 1116 |
| Synonyms | GMD; SDR3E1 |
| Locus ID | 2762 |
| UniProt ID | O60547 |
| Cytogenetics | 6p25.3 |
| Summary | GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).supplied by OMIM, Aug 2009 |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Metabolic pathways |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GMDS" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419903 | Lyophilized GMDS HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419903 | Transient overexpression lysate of GDP-mannose 4,6-dehydratase (GMDS) (as WB positive control) | 100 ug |
$436.00
|
|
| TP300471 | Recombinant protein of human GDP-mannose 4,6-dehydratase (GMDS), 20 µg | 20 ug |
$867.00
|
|
Citations
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