ITGB3BP (NM_014288) Human Mass Spec Standard

SKU
PH300064
ITGB3BP MS Standard C13 and N15-labeled recombinant protein (NP_055103)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200064
Predicted MW 20.2 kDa
Protein Sequence
Protein Sequence
>RC200064 protein sequence
Red=Cloning site Green=Tags(s)

MPVKRSLKLDGLLEENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHP
SLTESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTK
ELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_055103
RefSeq Size 1019
RefSeq ORF 531
Synonyms CENP-R; CENPR; HSU37139; NRIF3; TAP20
Locus ID 23421
UniProt ID Q13352
Cytogenetics 1p31.3
Summary This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. provided by RefSeq, Sep 2011
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
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Other "ITGB3BP" proteins (3)
SKU Description Size Price
LC402304 Lyophilized ITGB3BP HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402304 Transient overexpression lysate of integrin beta 3 binding protein (beta3-endonexin) (ITGB3BP) (as WB positive control) 100 ug
$436.00
TP300064 Recombinant protein of human integrin beta 3 binding protein (beta3-endonexin) (ITGB3BP), 20 µg 20 ug
$737.00

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