GIT2 (NM_139201) Human Mass Spec Standard
$3,360.00
3 Weeks*
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC200045 |
| Predicted MW | 52.6 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_631940 |
| RefSeq Size | 2357 |
| RefSeq ORF | 1413 |
| Synonyms | CAT-2; CAT2; PKL |
| Locus ID | 9815 |
| UniProt ID | Q6FI58 |
| Cytogenetics | 12q24.11 |
| Summary | This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. provided by RefSeq, Sep 2008 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GIT2" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC408350 | Lyophilized GIT2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC415041 | Lyophilized GIT2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC427594 | Lyophilized GIT2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY408350 | Transient overexpression lysate of G protein-coupled receptor kinase interacting ArfGAP 2 (GIT2), transcript variant 4 (as WB positive control) | 100 ug |
$436.00
|
|
| LY415041 | Transient overexpression lysate of G protein-coupled receptor kinase interacting ArfGAP 2 (GIT2), transcript variant 3 (as WB positive control) | 100 ug |
$665.00
|
|
| LY427594 | Transient overexpression lysate of G protein-coupled receptor kinase interacting ArfGAP 2 (GIT2), transcript variant 6 (as WB positive control) | 100 ug |
$665.00
|
|
| TP300045 | Recombinant protein of human G protein-coupled receptor kinase interacting ArfGAP 2 (GIT2), transcript variant 4, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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