KAT8 (NM_032188) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC224748L1V
Lenti ORF particles, KAT8 (Myc-DDK-tagged)-Human MYST histone acetyltransferase 1 (MYST1), transcript variant 1, 200ul, >10^7 TU/mL
  $1,236.00
3 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol KAT8
Synonyms hMOF; LIGOWS; MOF; MYST1; ZC2HC8
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC224748).
ACCN NM_032188
ORF Size 1374 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_032188.2
RefSeq Size 1546 bp
RefSeq ORF 1377 bp
Locus ID 84148
UniProt ID Q9H7Z6
Cytogenetics 16p11.2
Domains CHROMO, MOZ_SAS
Protein Families Transcription Factors
MW 52.9 kDa
Summary This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2012
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Documents
Resources

file-alt Citations

TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function
Zhong, Li, Cai et al
Nucleic Acids Res. (2016)
AI Summary: OriGene’s TET1 cDNA (RC218608) was used as a key reagent for expressing TET1 protein in this study, enabling the authors to investigate TET1’s role in regulating histone acetylation, gene expression, and DNA repair.
Snippet: TET1 cDNA was purchased from Origene (RC218608), cDNA for hMOF(NM_032188), SIN3A (NM_001145357), and Histone H4 (NM_003541) were generated fromcDNA library and confirmed by DNA sequencing, and then subcloned into pcDNA3.0 vector, ... Cite SaveSaving
Showing 1-1 of 1 papers.
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