DNA2 (NM_001080449) Human Tagged ORF Clone Lentiviral Particle

SKU RC217395L3V

Lenti ORF particles, DNA2 (Myc-DDK tagged) - Human DNA replication helicase 2 homolog (yeast) (DNA2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: DNA2
• Synonyms: DNA2L; hDNA2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217395).
• ACCN: NM_001080449
• ORF Size: 3438 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001080449.1, NP_001073918.1
• RefSeq Size: 4416 bp
• RefSeq ORF: 3183 bp
• Locus ID: 1763
• UniProt ID: P51530
• Cytogenetics: 10q21.3
• Protein Pathways: DNA replication
• MW: 129.5 kDa
• Summary: This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]