DNA2 Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-100 Positive control: Human esophagus cancer Predicted cell location: Nucleus |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human DNA2 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Gene Name | DNA replication helicase/nuclease 2 |
| Database Link | |
| Background | This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. |
| Synonyms | DNA2L; FLJ10063; KIAA0083; MGC133297 |
| Reference Data | |
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