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BLM (NM_000057) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC216075L1V
Lenti ORF particles, BLM (Myc-DDK tagged) - Human Bloom syndrome, RecQ helicase-like (BLM), 200ul, >10^7 TU/mL
  $2,368.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol BLM
Synonyms BS; MGRISCE1; RECQ2; RECQL2; RECQL3
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC216075).
ACCN NM_000057
ORF Size 4251 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_000057.1
RefSeq Size 4437 bp
RefSeq ORF 4254 bp
Locus ID 641
UniProt ID P54132
Cytogenetics 15q26.1
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Homologous recombination
MW 158.8 kDa
Summary The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. provided by RefSeq, May 2020
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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