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PCCA (NM_000282) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC214832L1V
Lenti ORF particles, PCCA (Myc-DDK tagged) - Human propionyl CoA carboxylase, alpha polypeptide (PCCA), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL
  $1,550.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol PCCA
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214832).
ACCN NM_000282
ORF Size 2184 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_000282.2
RefSeq Size 2518 bp
RefSeq ORF 2187 bp
Locus ID 5095
UniProt ID P05165
Cytogenetics 13q32.3
Domains Biotin_carb_C, biotin_lipoyl, CPSase_L_chain, CPSase_L_D2
Protein Families Druggable Genome
Protein Pathways leucine and isoleucine degradation, Metabolic pathways, Propanoate metabolism, Valine
MW 80.06 kDa
Summary The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, May 2010
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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