BCL2L2 (NM_004050) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC211152L2V
Lenti ORF particles, BCL2L2 (mGFP-tagged) - Human BCL2-like 2 (BCL2L2), transcript variant 1, 200ul, >10^7 TU/mL
  $850.00
5 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol BCL2L2
Synonyms BCL-W; BCL2-L-2; BCLW; PPP1R51
Vector pLenti-C-mGFP
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC211152).
ACCN NM_004050
ORF Size 579 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_004050.2
RefSeq Size 3621 bp
RefSeq ORF 582 bp
Locus ID 599
UniProt ID Q92843
Cytogenetics 14q11.2
Domains Bcl-2, BH4
Protein Families Druggable Genome, Transmembrane
MW 20.8 kDa
Summary This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. provided by RefSeq, Dec 2010
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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