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CD10 (MME) (NM_007288) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC210961L4V
Lenti ORF particles, MME (mGFP-tagged) - Human membrane metallo-endopeptidase (MME), transcript variant 2a, 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
mGFP w/ Puro DDK w/ Puro
  $1,237.00
5 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol CD10
Synonyms CALLA; CD10; CMT2T; NEP; SCA43; SFE
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC210961).
ACCN NM_007288
ORF Size 2250 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_007288.2
RefSeq Size 5665 bp
RefSeq ORF 2253 bp
Locus ID 4311
UniProt ID P08473
Cytogenetics 3q25.2
Domains Peptidase_M13
Protein Families Druggable Genome, Protease, Transmembrane
Protein Pathways Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system
MW 85.5 kDa
Summary The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. provided by RefSeq, Aug 2017
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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