MAPRE1 (NM_012325) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | MAPRE1 |
| Synonyms | EB1 |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_012325 |
| ORF Size | 804 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_012325.1 |
| RefSeq Size | 2640 bp |
| RefSeq ORF | 807 bp |
| Locus ID | 22919 |
| UniProt ID | Q15691 |
| Cytogenetics | 20q11.21 |
| Domains | CH, EB1 |
| Protein Families | Druggable Genome |
| MW | 30 kDa |
| Summary | The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. provided by RefSeq, Jul 2008 |
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