HTRA3 (NM_053044) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC207810L4V
Lenti ORF particles, HTRA3 (mGFP-tagged) - Human HtrA serine peptidase 3 (HTRA3), 200ul, >10^7 TU/mL
  $1,236.00
5 Weeks*
Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol HTRA3
Synonyms Prsp; Tasp
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC207810).
ACCN NM_053044
ORF Size 1359 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_053044.2
RefSeq Size 2585 bp
RefSeq ORF 1362 bp
Locus ID 94031
UniProt ID P83110
Cytogenetics 4p16.1
Domains IB, kazal, PDZ, Tryp_SPc
Protein Families Druggable Genome, Protease, Secreted Protein
MW 48.4 kDa
Summary Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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