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AMBRA1 (NM_017749) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC206255L1V
Lenti ORF particles, AMBRA1 (Myc-DDK tagged) - Human autophagy/beclin-1 regulator 1 (AMBRA1), 200ul, >10^7 TU/mL
  $2,127.00
3 Weeks*
Bulk Requests & Clone Modifications

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Other products for "AMBRA1 or NM_017749"

Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol AMBRA1
Synonyms DCAF3; WDR94
Vector pLenti-C-Myc-DDK
Mammalian Cell Selection None
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206255).
ACCN NM_017749
ORF Size 3624 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_017749.2
RefSeq Size 5034 bp
RefSeq ORF 3627 bp
Locus ID 55626
UniProt ID Q9C0C7
Cytogenetics 11p11.2
MW 132.8 kDa
Summary Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources

file-alt Citations

Parkin interacts with Ambra1 to induce mitophagy
Van Humbeeck, Cornelissen, Hofkens et al
J. Neurosci. (2011) 31 (28), 10249-61 DOI: 10.1523/JNEUROSCI.1917-11.2011
Cited by 36
AI Summary: OriGene supplied the pCMV6-XL4 vector containing human Ambra1 cDNA with a C-terminal Myc–FLAG tag and the pCMV6 Entry vector with untagged human Ambra1 cDNA, which were used to study the interaction between Parkin and Ambra1 in mitophagy.
Snippet: A pCMV6–XL4 vector containing human Ambra1 cDNA with a C-terminal Myc—FLAG tag and a pCMV6 Entry vector containing untagged human Ambra1 cDNA were purchased from Origene and verified by sequencing and WB.
Showing 1-1 of 1 papers.
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