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MSH2 (NM_000251) Human Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
RC205848L4V
Lenti ORF particles, MSH2 (mGFP-tagged) - Human mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2), 200ul, >10^7 TU/mL
file-pdf Biosafety Sheet
ORF Plasmid:
DDK tGFP
Lentiviral Particles:
mGFP w/ Puro DDK mGFP DDK w/ Puro
  $1,405.00
3 Weeks*
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Specifications
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol MSH2
Synonyms COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC205848).
ACCN NM_000251
ORF Size 2802 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_000251.1
RefSeq Size 3226 bp
RefSeq ORF 2805 bp
Locus ID 4436
UniProt ID P43246
Cytogenetics 2p21-p16.3
Domains MutS_I, MutS_II, MutS_III, MutS_IV, MutS_V
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Colorectal cancer, Mismatch repair, Pathways in cancer
MW 104.7 kDa
Summary This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2012
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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