EBP50 (SLC9A3R1) (NM_004252) Human Tagged ORF Clone Lentiviral Particle
- LentiORF®
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Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
|---|---|
| Tag | Myc-DDK |
| Target Symbol | EBP50 |
| Synonyms | EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2 |
| Vector | pLenti-C-Myc-DDK |
| Mammalian Cell Selection | None |
| Sequence Data | |
| ACCN | NM_004252 |
| ORF Size | 1074 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NM_004252.1 |
| RefSeq Size | 2032 bp |
| RefSeq ORF | 1077 bp |
| Locus ID | 9368 |
| UniProt ID | O14745 |
| Cytogenetics | 17q25.1 |
| Domains | PDZ |
| Protein Families | Druggable Genome |
| MW | 38.9 kDa |
| Summary | This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.provided by RefSeq, Sep 2009 |
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