DHRS11 (NM_024308) Human Tagged ORF Clone Lentiviral Particle

SKU RC201307L4V

Lenti ORF particles, DHRS11 (mGFP-tagged) - Human dehydrogenase/reductase (SDR family) member 11 (DHRS11), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: DHRS11
• Synonyms: ARPG836; SDR24C1; spDHRS11
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201307).
• ACCN: NM_024308
• ORF Size: 780 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_024308.3
• RefSeq Size: 1608 bp
• RefSeq ORF: 783 bp
• Locus ID: 79154
• UniProt ID: Q6UWP2
• Cytogenetics: 17q12
• Domains: adh_short
• Protein Families: Druggable Genome, Transmembrane
• MW: 28.3 kDa
• Summary: Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.[UniProtKB/Swiss-Prot Function]